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249,251 Dyslipidemia also affects Schwann cells, leading to mitochondrial dysfunction, endoplasmic reticulum stress, and oxidative stress, ultimately causing cell death

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In vitro data predict that at clinically relevant concentrations, other NSAIDs (naproxen, diclofenac, celecoxib) would not inhibit the uptake of pemetrexed by OAT3 and would not increase the AUC of pemetrexed to a clinically significant extent